What can cause a blister on my upper thigh?

Answer by  elynne (1153)

Chafing from your clothes or your underware can cause blisters. Sun exposure, chemical reactions to creams, tanning lotions. Numerous things, you have to take a look at your recent behavior

Answer by  monkeyz (3150)

It could be the result of too much contact with something. If you wear tight pants, pantyhose, or underwear that rubs the same area over and over, it could cause blistering. And there is always the possibility, if you are sexually active, of STDs being the cause.

Answer by  muzic74 (72)

Contact dermatitis caused by sweat or friction around the groin area could be a cause for blisters. In addition, a clogged sweat gland could also cause a blister like sore.

Answer by  DrAnishakap (22)

Some kind of a local infection may cause a blister on your upper thigh. If its a cluster of blisters filled with fluid and painful,then it may be herpes. An insect bite can also cause a blister. If it spreads or persists for more than 4-5 days then please consult a doctor

Answer by  YellowCup (1650)

More than likely an article of clothing you are wearing is tight and rubbing on your upper thigh causing an irritation.